Adenosine promotes human hair growth and inhibits catagen transition in vitro – role of the outer root sheath keratinocytes.Lisztes E et al., J Invest Dermatol, 2020It is well known that adenosine promotes human hair growth. In this study, together with our Hungarian collaborators, we unravel a novel mechanism by which […]
It is long known that adenosine promotes hair growth. One of the proposed mechanism involves the regulation of hair cycle-associated growth factors production and release by dermal papilla fibroblasts. However, full characterization of the cellular mechanism by which adenosine regulates hair growth cycle, and the distribution of adenosine receptors […]
An osteopontin-derived peptide inhibits human hair growth at least in part by decreasing FGF7 production in outer root sheath keratinocytes. Alam M. et al., Br J Dermatol, 2019 Osteopontin, a multifunctional immunomodulatory glycoprotein is expressed in human hair follicles. In this study a peptide fragment of OPN, FOL005 was investigated […]
Previous studies examining the topical application of theophylline in murine skin showed photodamage-protective properties (1). However, the effects of theophylline on human skin remains elusive. By using cutting-edge microscopy techniques and ex vivo assays, the research team at Monasterium Laboratory GmbH has investigated the in-depth effect of theophylline administration on […]
